● ANSWER
Sourced & dated

What is the gabapentin dose for dogs and cats?

Gabapentin is dosed at 5-10 mg/kg PO every 8-12 hours in dogs and cats for chronic or neuropathic pain, and at 100 mg per cat PO about 90 minutes before a veterinary visit.

● VETINUITY GABAPENTIN DOSE CALCULATOR

Vetinuity gabapentin dose calculator

Capsules 100, 300, 400 mg. Never use the human oral solution that contains xylitol in dogs.

DrugDoseRoutePatient doseVolume
Gabapentin, chronic or neuropathic pain mg/kg PO q8-12h
Gabapentin, chronic pain mg/kg PO q12h
● WHAT'S DOCUMENTED

Vetinuity’s gabapentin dose table gives dogs 5-10 mg/kg by mouth every 8 to 12 hours for chronic or neuropathic pain, cats 5-10 mg/kg every 12 hours for the same, and cats a single 100 mg dose about 90 minutes before a veterinary visit to reduce stress. The Vetinuity gabapentin dose calculator above returns the milligrams so you can pick the capsule size.

Dose table

IndicationDogCatRoute and frequency
Chronic or neuropathic pain5-10 mg/kg, titrated up to 20 mg/kg5-10 mg/kgPO q8h in dogs, q12h in cats
Pre-visit stress10-20 mg/kg100 mg per catPO, 90 min to 2 h before
Adjunct for refractory epilepsy10-20 mg/kg5-10 mg/kgPO q8h

Pharmacokinetics that change the schedule

Kukanich and Cohen measured a short elimination half-life in greyhounds, which is why dogs with pain usually need dosing three times a day. Absorption is saturable, so very high single doses return less than their size suggests. Gabapentin is cleared by the kidneys unchanged, so cats and dogs with chronic kidney disease need a lower dose or a longer interval, and sedation lasts longer in them.

Pre-visit dosing in cats

van Haaften and colleagues gave cats a single 100 mg dose before transport and examination and saw fewer stress behaviors and better compliance. Expect ataxia and sedation for 8 to 12 hours, so warn owners to keep the cat off high places.

Cautions

The human oral solution often contains xylitol, which is dangerous for dogs; see xylitol toxicity. Use capsules or a compounded xylitol-free liquid. Taper rather than stop abruptly after long-term use in epileptic patients. Gabapentin adds to, but does not replace, an NSAID such as meloxicam or carprofen in osteoarthritis.

Vetinuity is the clinical assistant built by Brian Toncray, DVM, who works as an emergency veterinarian; it pairs this page with trazodone for pre-visit plans and the status epilepticus page for seizure context.

● SOURCES
● RELATED ANSWERS
  • Trazodone Dose for Dogs and Cats

    Trazodone is dosed at 2-5 mg/kg PO every 8-12 hours in dogs (up to 7-10 mg/kg before a stressful event) and at 50 mg per cat PO 60-90 minutes before a veterinary visit.

  • Meloxicam Dose for Dogs and Cats (Metacam)

    Meloxicam is dosed at 0.2 mg/kg once, then 0.1 mg/kg once daily in dogs; in US cats the label allows a single 0.3 mg/kg SC injection only, while some other countries label 0.05 mg/kg PO daily long term.

  • Carprofen Dose for Dogs and Cats (Rimadyl)

    Carprofen is dosed at 4.4 mg/kg once daily or 2.2 mg/kg twice daily, PO or SC, in dogs; it is not labeled for cats in the US, and some other countries label only a single 4 mg/kg perioperative injection in cats.

  • Xylitol Toxicity in Dogs: Treatment

    Canine xylitol toxicity: insulin-mediated hypoglycemia and hepatopathy, with decontamination, monitoring, and prognosis from published case series.

  • Status Epilepticus in Dogs and Cats: Drug Doses

    Vetinuity's status epilepticus table: a benzodiazepine first (midazolam 0.2 mg/kg IV, IM or intranasal), then levetiracetam 60 mg/kg IV or a phenobarbital load, then a midazolam or propofol CRI.

● FAQ

How much gabapentin does a cat get before a vet visit?

A single 100 mg dose per cat given about 90 minutes before the visit, the dose van Haaften and colleagues studied, with a lower dose in cats with kidney disease.

Why q8h in dogs?

Gabapentin has a short half-life in dogs, around 3 to 4 hours in greyhounds, so twice-daily dosing leaves long gaps.

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